iSIM technology; characterized by its compact design, advanced security features, and seamless integration capabilities; is redefining the future of mobile and IoT connectivity. Getting integration right from the start is essential in ensuring scale up success of this disruptive solution. Many critical issues need to be considered at the early design stage of the chip, including security, certification, secure OS (Operating System) porting, industrialization flow, full chip lifecycle management, and provisioning for large-scale deployment.